NAC (N-Acetyl-L-Cysteine)

by Allergy Research Group


An antioxidant closely related to L-cysteine, being its acetyl derivative. Cysteine is important for homeostasis, being a key antioxidant, a glutathione precursor, and a natural source of sulfur for metabolism. Yet L-cysteine is unstable, and can become degraded while being absorbed. N-Acetyl Cysteine, on the other hand, is more stable than L-cysteine and conveniently becomes converted into L-cysteine after being absorbed. Thus NAC taken orally will raise blood and tissue cysteine levels. As a dietary supplement, NAC is therefore a highly attractive alternative to L-cysteine.

Dr. Hoffman considers NAC to be a premiere antioxidant, and favors its use as the most orally absorbable glutathione precursor.


Each tablet contains: N-Acetyl-L-Cysteine 500 mg Available in bottles of 90 tablets. Hypoallergenic.

Suggested Use: As a dietary supplement, one (1) tablet one to three times per day, or as directed by a health practitioner.


The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide medical advice to individuals. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


Qty Description Price
500 mg, 120 tablets $16.60

View Your Shopping Cart Items

Click here
information sheet by Allergy Research Group

Click here for more information on N-Acetyl Cysteine
"Glutathione Therapy," An interview with Dr. David Perlmutter by Jill Selby

Click here for more information on N-acetyl cysteine
Plant Sterols and Sterolins: Potential Immune System Modulators by Hoffman Center Staff

Click here for more information on N-acetyl cysteine
SUPPLEMENTS FOR SURGERY by Dr. Ronald L. Hoffman, M.D., CNS

Click here for more information on N-acetylcysteine
Alzheimer's Disease by Ronald Hoffman MD, CNS

Click here for more information on N-acetylcysteine
Asthma Update by Ronald Hoffman, M.D., C.N.S.

Click here for more information on N-acetylcysteine
Cataracts: Inevitable or Avoidable? by Abel, Jr., M.D.

Click here for more information on N-Acetyl-L-Cysteine
Allergies: The Natural Approach by The Standard

Click here for more information on N-Acetyl-L-Cysteine
Free Radicals, Antioxidants And Eye Diseases: Not As Incurable As We Once Thought by The Standard

Click here for more information on N-Acetyl-L-Cysteine
Managing Cholesterol: Naturally by The Standard

Click here for more information on NAC
Atherosclerosis by Leyla Muedin, RD, CDN

Click here for more information on NAC
Chronic Obstructive Pulmonary Disease By Ronald L. Hoffman, MD, CNS and Leyla Muedin, RD, CDN

Click here for more information on NAC
Fatty Liver Disease by Leyla Muedin, RD, CDN

Click here for more information on NAC
Hepatitis by Leyla Muedin, RD, CDN

High-dose N-acetylcysteine Helps Prevent Contrast-Induced Nephropathy
Am J Med, 2009; 122(9): 874-e9-15

Intravenous N-Acetylcysteine Administration During Hemodialysis May Improve Arterial Vascular Reacti
Nephron Clin Pract, 2009; 112(3): c184-9

N-acetylcysteine Improves Mismatch Negativity (MMN) in Persons with Schizophrenia
Neuropsychopharmacology, 2008; 33(9): 2187-99

N-Acetylcysteine May Reduce Depressive Symptoms in Persons with Bipolar Disorder
Biol Psychiatry, 2008 June 4; [Epub ahead of print]

N-Acetylcysteine More Effective Than Ascorbic Acid in Reducing Incidence of Contrast-Induced Nephro
American Heart Journal, 2009; DOI: 10.1016/j.ahj.2008.11.010

N-Acetylcysteine (NAC) in the Treatment of Noise-Induced Hearing Loss
Med Sci Monit, 2008; 14(8): BR159-64

N-Acetylcysteine Treatment May Reduce the Incidence of Postoperative Atrial Fibrillation
Eur Heart J, 2008; 29(5): 625-31

NAC Supplementation May Improve Physical Performance in Patients with COPD
Chest. 2009 May 15; [Epub ahead of print]

Supplementation with L-Arginine and N-acetylcysteine may Benefit Women with PCOS
J Endocrinol Invest, 2009 Apr 15;[Epub ahead of print]

Supplementation with N-Acetylcysteine May Benefit Men with Idiopathic Infertility
Urology, 2009; 74(1): 73-6

Supplementation with N-acetylcysteine May Reduce Trichotillomania Symptoms
Arch Gen Psychiatry, 2009; 66(7): 756-63

Topical N-Acetylcysteine Application May Enable Corneal Wound Healing After LASEK
Eur J Ophthalmol, 2009; 19(4): 554-9

Advanced Search:
Browse Products by Structure/Function

Know what you want? Skip ahead:
Order now!

Need to know more?
Our policies.